This article provides an overview of the policy hurdles for multiple micronutrient supplements (MMS) in South Africa; addresses the knowledge gap around the evidence base by taking the birth outcomes and cost-effectiveness of MMS from two recent scientific reviews, and applying it to the South African context; addresses the knowledge gap around programmatic aspects of MMS and synthesizes learnings from provinces to establish a transition back to MMS; and presents recommendations and strategies for the reintroduction of MMS into the World Health Organization’s (WHO) Essential Medicines List (EML).
