The objectives of the review are to (1) review the evidence on the burden of micronutrient deficiencies in women of reproductive age (WRA) and associated adverse pregnancy outcomes; (2) update the evidence base on the effects of Multiple Micronutrient Supplements (MMS) on pregnancy outcomes; (3) assess the costs and cost‐effectiveness of shifting from Iron Folic Acid (IFA) to MMS during pregnancy; and (4) provide indicators based on the updated evidence base that might be considered by governments deciding whether IFA or MMS is the most appropriate supplement for their contexts.