This cluster-randomized, controlled trial in Indramayu, Indonesia evaluates the efficacy of prenatal multiple micronutrient supplementation (MMS) for improving birth size, pregnancy outcome, and maternal micronutrient status in comparison with iron–folic acid (IFA) supplementation. It involved 843 pregnant women. Of these, 432 received MMS and 411 received IFA. Fieldworkers visited the women daily to observe supplement consumption and record fetal loss and mortality. Authors conclude that MMS use among pregnant women is as effective as IFA in improving anemia status and appears to have other benefits for maternal and child nutritional status.