This systematic review assessed the effectiveness of interventions designed to increase adherence to prenatal micronutrient supplementation. Interventions that resulted in increased adherence were most of the education‐based strategies, consumption monitoring by volunteer health workers or family members, SMS reminders, free provision of supplements, a multicomponent intervention with community mobilization, and a participatory action research intervention. In several studies, increased adherence was accompanied by beneficial effects on pregnancy and birth outcomes. Several potentially effective strategies were identified to improve supplementation adherence, which may need to be adapted to specific contexts when considered for program implementation.
